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Merck & Co has announced that in the pivotal phase III efficacy study, its investigational 9-valent HPV vaccine ( V503 ) prevented approximately 97% of cervical, vaginal and vulvar pre-cancers cau ...


Pfizer has announced that the Community-Acquired Pneumonia Immunization Trial in Adults ( CAPiTA ), the landmark study of approximately 85,000 subjects evaluating the efficacy of Prevenar 13 ( pneumoc ...


The possible risk of Guillain-Barré syndrome from influenza vaccines remains a potential obstacle to achieving high vaccination coverage. However, influenza infection might also be associated with Gui ...


Enterovirus 71 ( EV71 ) outbreaks are a socioeconomic burden, especially in the western Pacific region. Results of phase 1 clinical trials suggest an EV71 vaccine has a clinically acceptable safety pr ...


BCG vaccination provides incomplete protection against tuberculosis in infants. A new vaccine, modified Vaccinia Ankara virus expressing antigen 85A ( MVA85A ), was designed to enhance the protective ...


A vaccine for enterovirus 71 ( EV71 ) is needed to address the high burden of disease associated with infection. Researchers have assessed the efficacy, safety, immunogenicity, antibody persistence, a ...


A safe and effective vaccine for the prevention of human immunodeficiency virus type 1 ( HIV-1 ) infection is a global priority.Researchers have tested the efficacy of a DNA prime-recombinant adenovir ...


The influenza A(H1N1) 2009 monovalent vaccination programme was the largest mass vaccination initiative in recent US history. Commensurate with the size and scope of the vaccination programme, a proje ...


The candidate malaria vaccine RTS,S/AS01E has entered phase 3 trials, but data on long-term outcomes are limited.For 4 years, researchers followed children who had been randomly assigned, at 5 to 17 m ...


During the 2009 influenza A (H1N1) pandemic, pregnant women were at risk for severe influenza illness. This concern was complicated by questions about vaccine safety in pregnant women that were raised ...


A new study is helping to provide a better understanding of vaccines for whooping cough, the common name for the disease pertussis. Based on an animal model, the study conducted by the FDA ( Food and ...


The Committee for Medicinal Products for Human Use ( CHMP ) has finalised its assessment of an application to extend the use of Menveo to infants aged 2 to 23 months. The CHMP did not consider the res ...


Acellular pertussis vaccines effectively prevent pertussis in vaccinated individuals, but may fail to prevent colonization and transmission to uninfected individuals, according to a study. Acellular v ...


Initial vaccinations for human papillomavirus ( HPV ) at a young age is important for maximizing quadrivalent HPV vaccine effectiveness according to a Swedish study.HPV vaccination programs have been ...


Numerous studies have shown that inflammation has a relevant role in the pathogenesis of atherosclerosis as well as of acute coronary syndromes. Moreover, markers of inflammation predict cardiovascul ...